What Is PGS And PGD?

In the field of reproductive medicine, two key genetic screening techniques have transformed the success rates of IVF: Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD). Both these procedures allow fertility experts to identify chromosomal abnormalities or genetic disorders in embryos before implantation, significantly improving the chances of a successful pregnancy. If you’re considering IVF in Ahmedabad or any other region, understanding the nuances of PGS and PGD can help you make informed decisions.

What is PGS?

An approach called preimplantation genetic screening (PGS) is used to check for chromosomal abnormalities in developing embryos. It involves evaluating the number of chromosomes in the embryos to detect issues like aneuploidy, where there are missing or extra chromosomes. This abnormality can lead to miscarriages or conditions like Down syndrome.

How Does PGS Work?

PGS is typically done during an IVF cycle. After eggs are retrieved and fertilized, embryos are allowed to develop to the blastocyst stage, usually on day five or six. At this stage, a few cells are biopsied from each embryo, and these cells are sent for genetic testing. This process does not harm the embryo, and it continues to grow normally. The test results allow the fertility specialist to select embryos with the correct number of chromosomes for implantation, maximizing the chances of a healthy pregnancy.

For couples undergoing IVF in Ahmedabad, opting for clinics that offer PGS can significantly improve the success rates of the procedure. Top IVF centers in Ahmedabad use this advanced technology to ensure that only the healthiest embryos are transferred, leading to higher implantation success and fewer chances of miscarriage.

What is PGD?

Preimplantation Genetic Diagnosis (PGD), on the other hand, is used to identify specific genetic diseases or conditions in embryos. PGD is particularly valuable for couples who are carriers of inheritable genetic disorders such as cystic fibrosis, Tay-Sachs disease, or sickle cell anemia. Unlike PGS, which screens for chromosomal abnormalities, PGD targets specific genes to detect known hereditary conditions.

How Does PGD Work?

Similar to PGS, PGD involves extracting a few cells from the embryo at the blastocyst stage. However, instead of analyzing chromosome numbers, PGD looks for specific genetic markers that indicate the presence of a disease. Subsequently, the embryos devoid of the genetic abnormality are chosen for implantation.

Couples at top IVF centers in Ahmedabad, particularly those with a history of genetic disorders, may benefit greatly from PGD. The technology allows fertility experts to ensure that only healthy embryos are used in the IVF process, reducing the risk of passing on genetic disorders to the child.

Key Differences Between PGS and PGD

Although both PGS and PGD involve genetic testing of embryos, they serve different purposes:

PGS checks for chromosomal abnormalities, such as extra or missing chromosomes.

PGD tests for specific genetic diseases, making it essential for couples with known genetic risks.

When undergoing IVF in Ahmedabad, consulting with your fertility specialist about whether PGS or PGD is appropriate for your situation is crucial. The best IVF centers in Ahmedabad are equipped with the latest technology to perform both PGS and PGD, ensuring that the IVF process is as efficient and successful as possible.

Who Should Consider PGS and PGD?

PGS and PGD are recommended for different groups of people. Knowing which one is suitable for your situation can help improve your IVF success rate.

Candidates for PGS:

• Couples with recurrent miscarriages.
• IVF patients who are older than 35.
• Couples with failed IVF attempts.
• Those seeking to improve the success rate of IVF by selecting chromosomally normal embryos.

Candidates for PGD:

• Couples who are carriers of inheritable genetic disorders.
• Families with a history of specific genetic conditions such as Huntington’s disease, cystic fibrosis, or muscular dystrophy.
• Couples who wish to avoid passing on a known genetic disease to their child.

For those considering these advanced screening methods in Ahmedabad, several IVF centers in the city, including the best IVF center in Ahmedabad, offer both PGS and PGD. These procedures can dramatically increase the chances of a successful pregnancy, especially for couples with a history of genetic issues or multiple IVF failures.

Benefits of PGS and PGD in IVF

1. Improved Success Rates:

The top IVF centers in Ahmedabad that incorporate PGS and PGD into their fertility treatments report higher success rates. By ensuring that only chromosomally normal or genetically healthy embryos are implanted, couples are more likely to experience a successful pregnancy.

2. Reduced Risk of Miscarriage:

PGS reduces the risk of miscarriage by screening out embryos with chromosomal abnormalities. For older women or couples who have experienced past miscarriages, this is especially crucial.

3. Avoidance of Genetic Disorders:

PGD offers peace of mind for couples with a family history of genetic conditions. It is possible to reduce the chance of passing on inherited disorders by screening embryos for particular genetic abnormalities.

4. Cost-Effective in the Long Run:

Even while PGS or PGD may raise the initial cost of IVF in Ahmedabad, it frequently ends up being more affordable in the long run. By reducing the risk of failed IVF cycles and miscarriages, couples can avoid the emotional and financial toll of repeated treatments.

Selecting the Appropriate IVF Facility for PGD and PGS

Ahmedabad, Gujarat, is home to some of India’s top IVF centers, many of which are equipped to perform both PGS and PGD. When selecting an IVF center in Ahmedabad, it’s essential to consider factors like success rates, the expertise of the medical team, and the availability of advanced genetic screening technologies.

The best IVF center in Ahmedabad will offer comprehensive genetic counseling along with these screening services. For those looking to access cutting-edge fertility treatments, the top 5 IVF centers in Gujarat and the top 10 IVF centers in India often provide PGS and PGD as part of their services, ensuring that patients receive the highest level of care.